Rewiring life: using synthetic biology and experimental evolution to unravel the evolutionary origins of DNA.
Professor AM Poole at the launch of Te Ao Marama
We are extremely happy to have secured funds for this project, together researchers from the University of Auckland, Massey University and Kyoto University in Japan. Many have speculated on the origin of DNA, with its distinctive double helix, so it is truly exciting that we have an opportunity to experimentally delve into its evolutionary origins. We now have three years of hard work in front of us!
Professor Anthony Poole, discussing the newly received grant.
The following is an excerpt from the press release related to the grant.
“There are unmistakable signatures of past natural selection in both the choice of the four ‘letters’ with which genetic information is stored in DNA and the processes by which these letters are synthesised. However, we know surprisingly little about the pathway of trial and error that brought us to modern DNA, a seemingly optimal solution shared by all life. To unravel the origins of DNA and broaden our knowledge of genetic materials, we will use synthetic biology tools to recreate two of the critical intermediate ...